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Genetics of Prostate Cancer (PDQ®)

  • Posted: 11/20/2003
  • Updated: 07/18/2014

Table 14. Summary of Cross-Sectional Studies of Prostate Cancer Risk Perception

Study Population Sample Size Proportion of Study Population That Accurately Reported Their Risk Other Findings 
FDR = first-degree relative.
Unaffected men with a family history of prostate cancer [3]120 men aged 40–72 y40%
FDR of men with prostate cancer [4]105 men aged 40–70 y62%
Men with brothers affected with prostate cancer [5]111 men aged 33–78 yNot available38% of men reported their risk of prostate cancer to be the same or less than the average man.
FDR of men with prostate cancer and a community sample [6]56 men with an FDR with prostate cancer and 100 men without an FDR with prostate cancer all older than 40 y57%29% of men with an FDR thought that they were at the same risk as the average man, and 14% believed that they were at somewhat lower risk than average.

References

  1. Bratt O, Damber JE, Emanuelsson M, et al.: Risk perception, screening practice and interest in genetic testing among unaffected men in families with hereditary prostate cancer. Eur J Cancer 36 (2): 235-41, 2000.  [PUBMED Abstract]

  2. Cormier L, Kwan L, Reid K, et al.: Knowledge and beliefs among brothers and sons of men with prostate cancer. Urology 59 (6): 895-900, 2002.  [PUBMED Abstract]

  3. Beebe-Dimmer JL, Wood DP Jr, Gruber SB, et al.: Risk perception and concern among brothers of men with prostate carcinoma. Cancer 100 (7): 1537-44, 2004.  [PUBMED Abstract]

  4. Miller SM, Diefenbach MA, Kruus LK, et al.: Psychological and screening profiles of first-degree relatives of prostate cancer patients. J Behav Med 24 (3): 247-58, 2001.  [PUBMED Abstract]