Changes to This Summary (07/09/2014)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added National Comprehensive Cancer Network as reference 8.
Revised list of documentation typically needed for a cancer family history to include information from a mininum of first- and second-degree relatives on both the maternal and paternal sides of the family (cited Lu et al. as reference 34).
Revised list of clues that raise the suspicion of a hereditary cancer syndrome to include the presence of specific tumor types associated with germline mutations in cancer susceptibility genes, regardless of family history.
Revised text to state that clinical characteristics associated with distinctive risk ranges for multiple cancer genetic syndromes are summarized in the second edition of the Concise Handbook of Familial Cancer Susceptibility Syndromes.
This summary is written and maintained by the PDQ Cancer Genetics Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.