Evidence of Benefit
Prevention of Hepatitis B
Strong evidence that hepatocellular cancer (HCC) can be prevented is provided by a study of immunization to prevent transmission of hepatitis B from infected mothers to their children, suggesting that if hepatitis can be prevented, then much HCC can be prevented. Immunization programs are justified for preventing important short-term consequences of hepatitis B infection, such as acute hepatitis, chronic hepatitis, and cirrhosis.
- Chang MH, Chen CJ, Lai MS, et al.: Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 336 (26): 1855-9, 1997. [PUBMED Abstract]