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Liver (Hepatocellular) Cancer Prevention (PDQ®)

Health Professional Version
Last Modified: 02/27/2014

Evidence of Benefit

Prevention of Hepatitis B



Prevention of Hepatitis B

Strong evidence that hepatocellular cancer (HCC) can be prevented is provided by a study of immunization to prevent transmission of hepatitis B from infected mothers to their children, suggesting that if hepatitis can be prevented, then much HCC can be prevented. Immunization programs are justified for preventing important short-term consequences of hepatitis B infection, such as acute hepatitis, chronic hepatitis, and cirrhosis.[1]

References
  1. Chang MH, Chen CJ, Lai MS, et al.: Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 336 (26): 1855-9, 1997.  [PUBMED Abstract]