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Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ®)

  • Updated: 05/10/2012

Table 1. The Staging and Treatment of Newly Diagnosed or Recurrent Tumors According to Type of Tumor or Pathologic Subtype

Tumor Type Pathologic Subtype Staging and Treatment of Newly Diagnosed and Recurrent Disease 
CNS = central nervous system.
Astrocytomas and Other Tumors of Glial Origin
Low-Grade AstrocytomasDiffuse fibrillary astrocytomaChildhood Astrocytomas Treatment
Gemistocytic astrocytoma
Oligoastrocytoma
Oligodendroglioma
Pilocytic astrocytoma
Pilomyxoid astrocytoma
Pleomorphic xanthoastrocytoma
Protoplasmic astrocytoma
Subependymal giant cell astrocytoma
High-Grade AstrocytomasAnaplastic astrocytomaChildhood Astrocytomas Treatment
Anaplastic oligoastrocytoma
Anaplastic oligodendroglioma
Giant cell glioblastoma
Glioblastoma
Gliomatosis cerebri
Gliosarcoma
Brain Stem Glioma
Diffuse intrinsic pontine gliomasChildhood Brain Stem Glioma Treatment
Focal or low-grade brain stem gliomas
CNS Embryonal Tumors
MedulloblastomaAnaplasticChildhood CNS Embryonal Tumors Treatment
Classic
Desmoplastic/nodular
Large cell
Medulloblastoma with extensive nodularity
CNS Primitive Neuroectodermal Tumors (PNETs)CNS ganglioneuroblastoma
CNS neuroblastoma
Ependymoblastoma
Medulloepithelioma
Tumors of the Pineal RegionPineal parenchymal tumor of intermediate differentiation
Pineoblastoma
Pineocytoma
Papillary tumor of the pineal region
CNS Atypical Teratoid/Rhabdoid TumorChildhood CNS Atypical Teratoid/Rhabdoid Tumor Treatment
CNS Germ Cell Tumors
GerminomasChildhood CNS Germ Cell Tumors Treatment
TeratomasImmature teratomas
Mature teratomas
Teratomas with malignant transformation
Non-Germinomatous Germ Cell TumorsChoriocarcinoma
Embryonal carcinoma
Mixed germ cell tumors
Yolk sac tumor
Craniopharyngioma Childhood Craniopharyngioma Treatment
Ependymoma Childhood Ependymoma Treatment
Tumors of the Choroid Plexus