This page contains brief information about trametinib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Trametinib is approved to be used alone or with dabrafenib to treat:
- Melanoma that cannot be removed by surgery or has metastasized (spread to other parts of the body). It is used in patients who have certain mutations in the BRAF gene.
Trametinib is also being studied in the treatment of other types of cancer.
More About Trametinib
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Trametinib - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Targeted Cancer Therapies - Information about the use of this drug to treat cancer.
Clinical Trial Results: Combining Two Types of Targeted Therapy Improves Survival in Some Patients With Advanced Melanoma - Important clinical trial results for this drug, background information, and how the trial was done.
New Therapies Are Changing the Outlook for Advanced Melanoma - Information from NCI about this drug.
MEK: A Single Drug Target Shows Promise in Multiple Cancers - Information from NCI about this drug.
Clinical Trials Accepting Patients
Find Clinical Trials for Trametinib - Check for trials from NCI's list of cancer clinical trials now accepting patients.