Changes to This Summary (02/03/2012)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Updated statistics with estimated deaths for 2012 (cited American Cancer Society as reference 1).
Added text about a meta-analysis of double-blind, placebo-controlled, randomized trials that found that varenicline was associated with an increased risk of serious adverse cardiovascular events compared with placebo (cited Singh et al. as reference 30).

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