The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Significance ¹

Added text ¹ about systematic changes to the histological interpretation of biopsy specimens during the prostate-specific antigen screening era with the subsequent tendency by pathologists to read and treat high-grade tumors more aggressively (cited Albertsen et al. as reference 11 and Thompson et al. as reference 12).

Added statistics ² about reduced rates of metastases and disease-specific and overall mortalities to compare radical prostatectomy and surveillance in men with localized prostate cancer.

Opportunities for Prevention ³

Editorial changes were made to this section.