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Lung Cancer Screening (PDQ®)

  • Last Modified: 01/26/2012

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Changes to This Summary (01/26/2012)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Summary of Evidence

This section was extensively revised.

Significance

Updated statistics with estimated new cases and deaths for 2012 (cited American Cancer Society as reference 1).

Evidence of Benefit

Added the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial to the list of studies evaluating the most common screening tests for lung cancer (cited Oken et al. as reference 8).

Added text about the results of the PLCO Cancer Screening Trial, which found no evidence of lung cancer mortality reduction with screening using chest radiography compared with usual care.

Added text about the National Lung Screening Trial (NLST) (cited Aberle et al. as reference 31).

Added text about the results of the NLST.

Added text to state that other randomized controlled trials of LDCT are under way in a number of countries (cited Doria-Rose et al. as reference 45). Also added text about further analysis of the NLST.