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Chronic Myelogenous Leukemia Treatment (PDQ®)     
Last Modified: 06/26/2008
Health Professional Version
Changes to This Summary (06/26/2008)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Treatment Option Overview 1

Added Cortes et al. as reference 13 2, Kantarjian et al. [2007] as reference 14 2, and Guilhot et al. as reference 15 2.

Chronic-Phase Chronic Myelogenous Leukemia 3

Added text 4 about a prospective randomized study in which some patients with a matched related donor received early allogeneic stem cell transplantation versus interferon-based therapy and imatinib at relapse; some patients also underwent a matched unrelated donor transplant in remission and showed that survival favored the nonmatched donor arm with mostly early benefit (cited Hehlmann et al. as reference 35 and level of evidence 2A).

Blastic-Phase Chronic Myelogenous Leukemia 5

Added Fruehauf et al. as reference 4 6.

Relapsing Chronic Myelogenous Leukemia 7

Added Cortes et al. as reference 8 8, Kantarjian et al. [2007] as reference 9 8, and Guilhot et al. as reference 10 8.



Table of Links

1http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/19.cdr#Sect
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2http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/21.cdr#Sect
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3http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/26.cdr#Sect
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4http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/69.cdr#Sect
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5http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/48.cdr#Sect
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6http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/103.cdr#Sec
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7http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/56.cdr#Sect
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8http://cancer.gov/cancertopics/pdq/treatment/CML/HealthProfessional/162.cdr#Sec
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