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Adult Brain Tumors Treatment (PDQ®)

  • Updated: 02/28/2014

WHO Grades of CNS Tumorsa

 I II III IV 
a Reprinted with permission from Louis, DN, Ohgaki H, Wiestler, OD, Cavenee, WK. World Health Organization Classification of Tumours of the Nervous System. IARC, Lyon, 2007.
Astrocytic tumors
Subependymal giant cell astrocytomaX
Pilocytic astrocytomaX
Pilomyxoid astrocytomaX
Diffuse astrocytomaX
Pleomorphic xanthoastrocytomaX
Anaplastic astrocytomaX
GlioblastomaX
Giant cell glioblastomaX
GliosarcomaX
Oligondendroglial tumors
OligodendrogliomaX
Anaplastic oligodendrogliomaX
Oligoastrocytic tumors
OligoastrocytomaX
Anaplastic oligoastrocytomaX
Ependymal tumors
SubependymomaX
Myxopapillary ependymomaX
EpendymomaX
Anaplastic ependymomaX
Choroid plexus tumors
Choroid plexus papillomaX
Atypical choroid plexus papillomaX
Choroid plexus carcinomaX
Other neuroepithelial tumors
Angiocentric gliomaX
Chordoid glioma of the third ventricleX
Neuronal and mixed neuronal-glial tumors
GangliocytomaX
GangliogliomaX
Anaplastic gangliomaX
Desmoplastic infantile astrocytoma and gangliogliomaX
Dysembryoplastic neuroepithelial tumorX
Central neurocytomaX
Extraventricular neurocytomaX
Cerebellar liponeurocytomaX
Paraganglioma of the spinal cordX
Papillary glioneuronal tumorX
Rosette-forming glioneural tumor of the fourth ventricleX
Pineal tumors
PineocytomaX
Pineal parenchymal tumor of intermediate differentiationXX
PineoblastomaX
Papillary tumor of the pineal regionXX
Embryonal tumors
MedulloblastomaX
CNS primitive neuroectodermal tumor (PNET)X
Atypical teratoid/rhabdoid tumorX
Tumors of the cranial and paraspinal nerves
SchwannomaX
NeurofibromaX
PerineuriomaXXX
Malignant peripheral nerve sheath tumor (MPNST)XXX
Meningeal tumors
MeningiomaX
Atypical meningiomaX
Anaplastic/malignant meningiomaX
HemangiopericytomaX
Anaplastic hemangiopericytomaX
HemangioblastomaX
Tumors of the sellar region
CraniopharyngiomaX
Granular cell tumor of the neurohypophysisX
PituicytomaX
Spindle cell oncocytoma of the adenohypophysisX