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Anal Cancer Treatment (PDQ®)

  • Updated: 07/31/2014

Table 1. Primary Tumor (T)a

TXPrimary tumor cannot be assessed.
T0No evidence of primary tumor.
TisCarcinoma in situ (i.e., Bowen disease, high-grade squamous intraepithelial lesion, and anal intraepithelial neoplasia II–III.)
T1Tumor ≤2 cm in greatest dimension.
T2Tumor >2 cm but ≤5 cm in greatest dimension.
T3Tumor >5 cm in greatest dimension.
T4Tumor of any size invades adjacent organ(s), e.g., vagina, urethra, and bladder.b

aReprinted with permission from AJCC: Anus. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 165-73.
bDirect invasion of the rectal wall, perirectal skin, subcutaneous tissue, or the sphincter muscle(s) is not classified as T4.