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Childhood Craniopharyngioma Treatment (PDQ®)

Health Professional Version

Changes to This Summary (08/12/2014)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information

Revised text to state that between 1975 and 2010, childhood cancer mortality has decreased by more than 50% (cited Smith et al. as reference 3).

Stage Information

Revised text to state that for treatment purposes, patients are classified as having newly diagnosed or recurrent disease.

Treatment Options for Newly Diagnosed Childhood Craniopharyngioma

Revised text to state that there is no consensus as to the optimal treatment of newly diagnosed craniopharyngioma, in part due to the lack of prospective randomized trials comparing different treatment options. Also added text to state that a systematic review of 109 reports that described extent of resection found that subtotal resection plus radiation therapy was associated with similar rates of tumor control as gross total resection and that both approaches were associated with higher progression-free survival rates than subtotal resection; treatment is individualized based on factors such as the size, location, and extension of the tumor and potential short-term and long-term toxicity.

Late Effects in Patients Treated for Childhood Craniopharyngioma

Added text to state that patients with hypothalamic involvement showed impairment in memory and executive functioning (cited Özyurt et al. as reference 2).

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

  • Updated: August 12, 2014