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Childhood Central Nervous System Germ Cell Tumors Treatment (PDQ®)

  • Posted: 12/14/2011
  • Updated: 08/01/2013

Table 2. Serum and Cerebrospinal Fluid Markers

Tumor Type  Beta-HCG  AFP 
AFP = alpha-fetoprotein; HCG = human chorionic gonadotropin; + = positive; - = negative; ± = equivocal; +++ = strongly positive; (±) equivocal, not diagnostic; (+) = positive, not diagnostic.
Choriocarcinoma+++-
Embryonal carcinoma--
Germinoma(±)-
Teratoma-(+)
Yolk sac tumor-+++