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Childhood Central Nervous System Embryonal Tumors Treatment (PDQ®)     
Last Modified: 08/21/2008
Health Professional Version
Changes to This Summary (08/21/2008)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Purpose of this PDQ Summary 1

Added text 2 about the usage that accompanies some reference citations.

Staging of Medulloblastoma 3

Added text 4 about the level-of-evidence designation that follows some citations in the section

Cited Polkinghorn et al. as reference 25 5. [Level of evidence: 3iiiDi]

Cited Giangaspero et al. as reference 26 5. [Level of evidence: 3iiiDi]

Treatment Option Overview 6

Added text 6 about the level-of-evidence designation that follows some citations in the text.

Cited Stargatt et al. as reference 4 7. [Level of evidence: 3iC]

Cited Wolfe-Christensen et al. as reference 7 7. [Level of evidence: 3iiiC]

Treatment for Newly Diagnosed Childhood Medulloblastoma 8

Added text 9 about the level-of-evidence designation that follows some citations in the text.

Added text 10 about the COG phase III trial (COG-ACNS0332) for children aged 3 years and older.

Cited Sung et al. as reference 17 11. [Level of evidence: 2A]

Added text 12 about the COG phase III randomized trial (COG-ACNS0334) for children aged 3 years and younger with high-risk medulloblastoma or supratentorial primitive neuroectodermal tumors.

Treatment Options for Newly Diagnosed Pineoblastoma and Pineal Parenchymal Tumors of Intermediate Differentiation 13

Added text 14 about the level-of-evidence designation that follows some citations in the text.

Cited Fangusaro et al. as reference 5 15. [Level of evidence: 2Di]

Treatment Options for Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors 16

Added text 17 about the level-of-evidence designation that follows some citations in the text.

Added Children Aged 3 Years and Younger 18 as a new subsection.

Recurrent Childhood Central Nervous System Embryonal Tumors 19

Added text 20 about the level-of-evidence designation that follows some citations in the text.

Cited Bowers et al. as reference 14 21. [Level of evidence: 3iA]



Table of Links

1http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/196.cdr#Section_196
2http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/201.cdr#Section_201
3http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/14.cdr#Section_14
4http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/203.cdr#Section_203
5http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/22.cdr#Section_22
6http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/23.cdr#Section_23
7http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/25.cdr#Section_25
8http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/29.cdr#Section_29
9http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/205.cdr#Section_205
10http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/43.cdr#Section_43
11http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/47.cdr#Section_47
12http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/49.cdr#Section_49
13http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/52.cdr#Section_52
14http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/206.cdr#Section_206
15http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/60.cdr#Section_60
16http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/63.cdr#Section_63
17http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/207.cdr#Section_207
18http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/67.cdr#Section_67
19http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/71.cdr#Section_71
20http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/208.cdr#Section_208
21http://cancer.gov/cancertopics/pdq/treatment/childCNSembryonal/healthprofession
al/73.cdr#Section_73