Table 1. Gastrointestinal Neuroendocrine Cellsa
| Cell Type | Location | Secretory Product |
| G cell | Gastric antrum and duodenum | Gastrin |
| ECL cell | Gastric fundus and body | Histamine |
| D cell | Stomach, duodenum, jejunum, colon, and rectum | Somatostatin |
| EC cell | Stomach, duodenum, jejunum, ileum, colon, and rectum | Serotonin, motilin, and substance P |
| CCK cell | Duodenum and jejunum | Cholecystokinin |
| GIP cell | Duodenum and jejunum | Gastric inhibitory polypeptide |
| M cell | Duodenum and jejunum | Motilin |
| S cell | Duodenum and jejunum | Secretin |
| PP cell | Duodenum | Pancreatic polypeptide |
| L cell | Jejunum, ileum, colon, and rectum | Polypeptide YY |
| N cell | Jejunum and ileum | Neurotensin |
| CCK = cholecystokinin; D = somatostatin-producing; EC = enterochromaffin; ECL = enterochromaffin-like; G = Gastrin cell; GIP = gastric inhibitory polypeptide; L = enteroendocrine; M = motilin; N = neurotensin; PP = pancreatic polypeptide; S = secretin. | ||
| a Adapted from [1-3] |
References
- Levy AD, Sobin LH: From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison. Radiographics 27 (1): 237-57, 2007 Jan-Feb. [PUBMED Abstract]
- Burke AP, Thomas RM, Elsayed AM, et al.: Carcinoids of the jejunum and ileum: an immunohistochemical and clinicopathologic study of 167 cases. Cancer 79 (6): 1086-93, 1997. [PUBMED Abstract]
