In English | En español
Questions About Cancer? 1-800-4-CANCER

Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®)

  • Last Modified: 03/07/2014

Page Options

  • Print This Page
  • Print This Document
  • View Entire Document
  • Email This Document

Cellular Classification of Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)



Table 1. Endocrine Tumors of the Pancreas
Islet Cells Secreted Active Agent Tumor and Syndrome 
ACTH = adrenocorticotropin; MSH = melanocyte-stimulating hormone; VIP = vasoactive intestinal peptide; WDHA = watery diarrhea, hypokalemia, and achlorhydria; 5-HT = serotonin.
AlphaGlucagonGlucagonoma (diabetes, dermatitis)
BetaInsulinInsulinoma (hypoglycemia)
DeltaSomatostatinSomatostatinoma (mild diabetes); diarrhea/steatorrhea; gallstones
DGastrinGastrinoma (peptic ulcer disease)
A -> DVIP and/or other undefined mediatorsWDHA
5-HT
ACTH
MSHCarcinoid
Cushing syndrome
Hyperpigmentation
Interacinar Cells Secreted Active Agent Tumor and Syndrome
FPancreatic polypeptideMultiple hormonal syndromes
EC5-HTCarcinoid