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Malignant Mesothelioma Treatment (PDQ®)

Health Professional Version
Last Modified: 10/27/2011

Changes to This Summary (10/27/2011)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information About Malignant Mesothelioma Treatment 1

Added de Perrot et al. as reference 4 2.

Stage Information for Malignant Mesothelioma 3

Updated staging information 4 for 2010 (cited Edge et al. as reference 2).

Advanced Malignant Mesothelioma (Stages II, III, and IV) 5

Added de Perrot et al. as reference 12 6.

Added text 7 about a large randomized study from the United Kingdom (BTS-MRC-MS01 8) that compared active symptom control (ASC) with the chemotherapy regimens of mitomycin C, vinblastine, and cisplatin (MVP) or single-agent vinorelbine and showed that despite some changes to the original trial design, no significant difference in survival was detected between ASC and chemotherapy (cited Muers et al. as reference 17 and level of evidence 1iiA).

Table of Links

1http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/#Section_1
2http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/#Section_113
3http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/Page3#Section_5
4http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/Page3#Section_105
5http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/Page6#Section_29
6http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/Page6#Section_44
7http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/HealthPr
ofessional/Page6#Section_107
8http://www.cancer.gov/clinicaltrials/search/view?version=healthprofessional&
;cdrid=347461