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Merkel Cell Carcinoma Treatment (PDQ®)

  • Updated: 03/07/2014

Table 2. Five Previously Used Competing Merkel Cell Carcinoma Staging Systems

First Author Publication Date  Institution(s) No. of Patients in Case Series Dates of Cases 
Yiengpruksawan et al.[2]1991MSKCCa771969–1989
Allen et al.[3]1999MSKCCa1021969–1996
Allen et al.[4]2005MSKCCa2501970–2002
American Joint Committee on Cancer[5]2002N/AN/A
Clark et al.[6]2007Westmead Hospital, Sydney, Australia110
Princess Margaret Hospital/University Health Network, Toronto, Canada
Sydney Head and Neck Cancer Institute/Royal Prince Alfred Hospital, Sydney, Australia

MSKCC = Memorial Sloan Kettering Cancer Center; N/A = Not applicable.
aThe MSKCC system has evolved over time. MSKCC authors have published one additional case series with 256 patients.[1]


  1. Andea AA, Coit DG, Amin B, et al.: Merkel cell carcinoma: histologic features and prognosis. Cancer 113 (9): 2549-58, 2008.  [PUBMED Abstract]

  2. Yiengpruksawan A, Coit DG, Thaler HT, et al.: Merkel cell carcinoma. Prognosis and management. Arch Surg 126 (12): 1514-9, 1991.  [PUBMED Abstract]

  3. Allen PJ, Zhang ZF, Coit DG: Surgical management of Merkel cell carcinoma. Ann Surg 229 (1): 97-105, 1999.  [PUBMED Abstract]

  4. Allen PJ, Bowne WB, Jaques DP, et al.: Merkel cell carcinoma: prognosis and treatment of patients from a single institution. J Clin Oncol 23 (10): 2300-9, 2005.  [PUBMED Abstract]

  5. American Joint Committee on Cancer: AJCC Cancer Staging Manual. 6th ed. New York, NY: Springer, 2002. 

  6. Clark JR, Veness MJ, Gilbert R, et al.: Merkel cell carcinoma of the head and neck: is adjuvant radiotherapy necessary? Head Neck 29 (3): 249-57, 2007.  [PUBMED Abstract]