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Ovarian Germ Cell Tumors Treatment (PDQ®)

Health Professional Version
Last Modified: 03/07/2014

Cellular Classification of Ovarian Germ Cell Tumors

The following histologic subtypes have been described.[1,2]

  • Dysgerminoma.
  • Other germ cell tumors:
    • Endodermal sinus tumor (rare subtypes are hepatoid and intestinal).[1]
    • Embryonal carcinoma.
    • Polyembryoma.
    • Choriocarcinoma.
    • Teratoma:
      • Immature.
      • Mature:
        • Solid.
        • Cystic:
          • Dermoid cyst (mature cystic teratoma).
          • Dermoid cyst with malignant transformation.
      • Monodermal and highly specialized:
        • Struma ovarii.
        • Carcinoid.
        • Struma ovarii and carcinoid.
        • Others (e.g., malignant neuroectodermal and ependymoma).
    • Mixed forms.
  1. Gershenson DM: Update on malignant ovarian germ cell tumors. Cancer 71 (4 Suppl): 1581-90, 1993.  [PUBMED Abstract]

  2. Serov SF, Scully RE, Robin IH: International Histologic Classification of Tumours: No. 9. Histological Typing of Ovarian Tumours. Geneva: World Health Organization, 1973.