Questions About Cancer? 1-800-4-CANCER

Vaginal Cancer Treatment (PDQ®)

Health Professional Version
Last Modified: 07/28/2011

Stage IVA Vaginal Cancer

Squamous Cell Carcinoma
Adenocarcinoma
Current Clinical Trials



Squamous Cell Carcinoma

Standard treatment options:

  1. Combination of interstitial, intracavitary, and external-beam radiation therapy (EBRT).[1]
  2. Rarely, surgery may be combined with the above.[2]
Adenocarcinoma

Standard treatment options:

  1. Combination of interstitial, intracavitary, and EBRT.[1]
  2. Rarely, surgery may be combined with the above.
Current Clinical Trials

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IVA vaginal cancer 1. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site 2.

References

  1. Perez CA, Camel HM, Galakatos AE, et al.: Definitive irradiation in carcinoma of the vagina: long-term evaluation of results. Int J Radiat Oncol Biol Phys 15 (6): 1283-90, 1988.  [PUBMED Abstract]

  2. Boronow RC, Hickman BT, Reagan MT, et al.: Combined therapy as an alternative to exenteration for locally advanced vulvovaginal cancer. II. Results, complications, and dosimetric and surgical considerations. Am J Clin Oncol 10 (2): 171-81, 1987.  [PUBMED Abstract]



Table of Links

1http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?Diagnosis=38064&tt=1&a
mp;format=2&cn=1
2http://www.cancer.gov/clinicaltrials