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High-Dose Vitamin C (PDQ®)

Changes to This Summary (03/26/2015)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Laboratory/Animal/Preclinical Studies

Added text to state that this study used dehydroascorbate, the oxidized form of vitamin C that is known to be transported actively into cells and then reduced to vitamin C. Also added text to state that greater tumor volume seen in mice treated with oral vitamin C plus bortezomib was caused by a chemical reaction that occurs in the gastrointestinal tract but does not appear to be relevant to intravenous administration.

This summary is written and maintained by the PDQ Cancer Complementary and Alternative Medicine Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

  • Updated: March 26, 2015