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Milk Thistle (PDQ®)

  • Last Modified: 12/23/2013

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Changes to This Summary (12/23/2013)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Overview

Revised text to state that the active substance in milk thistle, silymarin, is a complex mixture of flavonolignans, primarily consisting of the following isomers: silybin (consisting of silybins A and B), isosilybin (consisting of isosilybins A and B), silychristin (also known as silichristin), and silydianin (also known as silidianin).

General Information

Revised text to state that the primary active constituent of milk thistle is silymarin, which is composed of the following isomers: silybin (consisting of silybins A and B), isosilybin (consisting of isosilybins A and B), silychristin, and silydianin (cited Napolitano et al. as reference 3).

This summary is written and maintained by the PDQ Cancer Complementary and Alternative Medicine Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.