Gene	Syndrome	Hereditary Pattern	Predominant Cancer
Adapted from Vogelstein et al.[2]
Tumor suppressor genes
APC (OMIM)	FAP (OMIM)	Dominant	Colon, intestine, etc.
AXIN2 (OMIM)	Attenuated Polyposis (OMIM)	Dominant	Colon
TP53 (p53) (OMIM)	Li-Fraumeni (OMIM)	Dominant	Multiple (including colon)
STK11 (OMIM)	Peutz-Jeghers (OMIM)	Dominant	Multiple (including intestine)
PTEN (OMIM)	Cowden (OMIM)	Dominant	Multiple (including intestine)
BMPR1A (OMIM)	Juvenile Polyposis (OMIM)	Dominant	Gastrointestinal
SMAD4 (DPC4) (OMIM)	Juvenile Polyposis (OMIM)	Dominant	Gastrointestinal
Repair/Stability genes
hMLH1 (OMIM), hMSH2(OMIM), hMSH6(OMIM), PMS2 (OMIM)	Lynch syndrome (OMIM)	Dominant	Multiple (including colon, uterus, and others)
MYH (MutYH) (OMIM)	Attenuated Polyposis (OMIM)	Recessive	Colon
BLM (OMIM)	Bloom (OMIM)	Recessive	Multiple (including colon)
Oncogenes
KIT (OMIM)	Familial GI Stromal Tumor (OMIM)		GI stromal tumors
PDGFRA (OMIM)	Familial GI Stromal Tumor (OMIM)		GI stromal tumors

References

2. Vogelstein B, Kinzler KW: Cancer genes and the pathways they control. Nat Med 10 (8): 789-99, 2004.  [PUBMED Abstract]