 |
|
|
Table 7C. Summary of Studies Evaluating Interest in or Intention to Have Genetic Counseling and Testing for Familial Adenomatous Polyposis (FAP)*
|
Study Population
|
N†
|
Interest or Intention in GC or GT‡
|
| FAP-affected individuals [16] |
25 |
60% prenatal GT interest; 18% would consider aborting fetus if mutation was found |
| FAP-affected individuals [17] |
62 |
65% prenatal GT interest; 24% would consider aborting fetus if mutation was found; 94% GT interest at birth |
|
*Both studies used a cross-sectional design and were conducted in the United Kingdom.[16,17]
|
|
†Indicates number of participants older than 18 years, unless otherwise specified.
|
|
‡Type of genetic test not specified.
|
References
-
Burn J, Chapman P, Delhanty J, et al.: The UK Northern region genetic register for familial adenomatous polyposis coli: use of age of onset, congenital hypertrophy of the retinal pigment epithelium, and DNA markers in risk calculations. J Med Genet 28 (5): 289-96, 1991.
[PUBMED Abstract]
-
Whitelaw S, Northover JM, Hodgson SV: Attitudes to predictive DNA testing in familial adenomatous polyposis. J Med Genet 33 (7): 540-3, 1996.
[PUBMED Abstract]
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|
|
