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Fatigue (PDQ®)

Changes to This Summary (08/28/2014)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Editorial and formatting changes were made to this summary.


Added the Multidimensional Fatigue Symptom Inventory-Short Form to the list of instruments used to assess fatigue (cited Stein et al. as reference 24).


Added text about a study that demonstrated that managing symptoms (e.g., pain, nausea, and decreased appetite) can have a significant positive impact on fatigue (cited de Raaf et al. as reference 5).

Added Other Pharmacologic Interventions as a new subsection.

Revised text to state that one fairly large study evaluated medical qigong for cancer-related fatigue in a heterogeneous group of 162 patients either undergoing cancer treatment or having finished cancer treatment.

Added text about a study of qigong to improve quality of life in women undergoing radiation therapy for breast cancer (cited Chen et al. as reference 57).

Added text to state that the major weakness limiting interpretation and integration of both of these studies, despite differing results, is that there was no attempt to control for attention or any of the social aspects of the intervention.

This summary is written and maintained by the PDQ Supportive and Palliative Care Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

  • Updated: August 28, 2014