The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Stage I, II, IIIA, and Operable IIIC Breast Cancer ¹

Added text ² about a Danish trial that compared ovarian ablation or suppression to cyclophosphamide, methotrexate, and fluorouracil in premenopausal, ER-positive women and found no difference in overall survival or disease-free survival in the two study groups; taxanes and anthracyclines were not included in the study (cited Ejlerstsen et al. as reference 129 and Wolff et al. as reference 130).

Added Moore et al. as reference 187 ³.

Added Tan-Chiu et al. as reference 196 ⁴.