Table 4. Distant Metastases (M)a
| aReprinted with permission from AJCC: Breast. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 347-76. | |
| M0 | No clinical or radiographic evidence of distant metastases. |
| cM0(i+) | No clinical or radiographic evidence of distant metastases, but deposits of molecularly or microscopically detected tumor cells in circulating blood, bone marrow, or other nonregional nodal tissue that are ≤0.2 mm in a patient without symptoms or signs of metastases. |
| M1 | Distant detectable metastases as determined by classic clinical and radiographic means and/or histologically proven >0.2 mm. |
