National Cancer Institute

at the National Institutes of Health

Endometrial Cancer Treatment (PDQ®)

Health Professional Version

Last Modified: 02/15/2013

Stage Information for Endometrial Cancer

Definitions: FIGO

The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) and the American Joint Committee on Cancer (AJCC) have designated staging to define endometrial cancer; the FIGO system is most commonly used.[1,2]

Carcinosarcomas should be staged as carcinoma.[2]

Table 1. Carcinoma of the Endometrium^a

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Stage
I^b	Tumor confined to the corpus uteri.
IA^b	No or less than half myometrial invasion.
IB^b	Invasion equal to or more than half of the myometrium.
II^b	Tumor invades cervical stroma but does not extend beyond the uterus.^c
III^b	Local and/or regional spread of the tumor.
IIIA^b	Tumor invades the serosa of the corpus uteri and/or adnexae.^d
IIIB^b	Vaginal and/or parametrial involvement.^d
IIIC^b	Metastases to pelvic and/or para-aortic lymph nodes.^d
IIIC1^b	Positive pelvic nodes.
IIIC2^b	Positive para-aortic lymph nodes with or without positive pelvic lymph nodes.
IV^b	Tumor invades bladder and/or bowel mucosa, and/or distant metastases.
IVA^b	Tumor invasion of bladder and/or bowel mucosa.
IVB^b	Distant metastases, including intra-abdominal metastases and/or inguinal lymph nodes.

^aAdapted from FIGO Committee on Gynecologic Oncology.[1]
^bEither G1, G2, or G3 (G = grade).
^cEndocervical glandular involvement only should be considered as stage I and no longer as stage II.
^dPositive cytology has to be reported separately without changing the stage.

References

Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 105 (2): 103-4, 2009. [PUBMED Abstract]
Corpus uteri. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 403-18.