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Childhood Extracranial Germ Cell Tumors Treatment (PDQ®)

  • Updated: 10/27/2014

Table 3. Histology of Malignant Germ Cell Tumors in Adolescents and Young Adultsa

Malignant Germ Cell Elements Location 
Yolk sac tumor (endodermal sinus tumor)E, O, T
ChoriocarcinomaE, O, T
Embryonal carcinomaE, T
Mixed germ cell tumorsE, O, T

E = extragonadal; O = ovarian; T = testicular.
aModified from Perlman et al.[23]


  1. Perlman EJ, Hawkins EP: Pediatric germ cell tumors: protocol update for pathologists. Pediatr Dev Pathol 1 (4): 328-35, 1998 Jul-Aug.  [PUBMED Abstract]