Changes to This Summary (02/03/2012)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information About Osteosarcoma and Malignant Fibrous Histiocytoma (MFH) of Bone

The Genetic diseases that predispose to osteosarcoma subsection was renamed from Inherited diseases that predispose to osteosarcoma.

Recurrent Osteosarcoma and MFH of Bone

Added text to state that in 564 patients with a recurrence, patients whose disease recurred within 2 years of diagnosis had a worse prognosis than did patients whose disease recurred after 2 years; patients with a good histologic response to initial preoperative chemotherapy had a better overall survival after recurrence than did poor responders (cited Gelderblom et al. as reference 1).