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Small Intestine Cancer Treatment (PDQ®)

Health Professional Version

Small Intestine Adenocarcinoma

Standard treatment options:

  1. For resectable primary disease:
    • Radical surgical resection.[1,2]
  2. For unresectable primary disease:
    • Surgical bypass of obstructing lesion.
    • Palliative radiation therapy.

Treatment options under clinical evaluation:

  1. For unresectable primary disease:
    • Clinical trials evaluating methods to improve local control, such as the use of radiation therapy with radiosensitizers with or without systemic chemotherapy.
  2. For unresectable metastatic disease:
    • Clinical trials evaluating the value of new anticancer drugs and biologicals (phase I and phase II studies).

Current Clinical Trials

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with small intestine adenocarcinoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References

  1. Rose DM, Hochwald SN, Klimstra DS, et al.: Primary duodenal adenocarcinoma: a ten-year experience with 79 patients. J Am Coll Surg 183 (2): 89-96, 1996. [PUBMED Abstract]
  2. North JH, Pack MS: Malignant tumors of the small intestine: a review of 144 cases. Am Surg 66 (1): 46-51, 2000. [PUBMED Abstract]
  • Updated: July 31, 2014