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Table 2. Standard Chemotherapy Regimens for Wilms Tumor

Regimen Name Regimen Description 
Regimen EE-4A [67]Vincristine, dactinomycin × 18 weeks postnephrectomy
Regimen DD-4A [67]Vincristine, dactinomycin, doxorubicin × 24 weeks; baseline nephrectomy or biopsy with subsequent nephrectomy
Regimen I [100]Vincristine, doxorubicin, cyclophosphamide, etoposide × 24 weeks postnephrectomy


  1. Grundy PE, Breslow NE, Li S, et al.: Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group. J Clin Oncol 23 (29): 7312-21, 2005.  [PUBMED Abstract]

  2. Dome JS, Cotton CA, Perlman EJ, et al.: Treatment of anaplastic histology Wilms' tumor: results from the fifth National Wilms' Tumor Study. J Clin Oncol 24 (15): 2352-8, 2006.  [PUBMED Abstract]