Changes to This Summary (12/08/2011)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Revised text to state that screening with abdominal ultrasound and serum alpha-fetoprotein is suggested until age 4 years; after the age of 4 years, most hepatoblastomas will have occurred, and imaging may be limited to renal ultrasound, which is faster and does not require the child to fast for the exam.
Added text to state that mesoblastic nephroma is the most common kidney tumor found in infants younger than 3 months (cited England et al. as reference 26).
Revised text to state that renal cell carcinomas have been described in patients several years after diagnosis and therapy for pediatric malignancies such as neuroblastoma, rhabdomyosarcoma, and leiomyosarcoma (cited Dhall et al., Schafernak et al., and Brassesco et al. as references 49, 50, and 52, respectively).
Added Zhuge et al. as reference 16.
Treatment of Congenital Mesoblastic Nephroma
Added text to state that in a report from the United Kingdom of 50 children with mesoblastic nephroma studied on clinical trials and 80 cases from the national registry in the same time period, there were no deaths (cited England et al. as reference 2).
Added text to state that although incompletely resected, stage III infants younger than 2 months may not need chemotherapy.
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