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Cardiopulmonary Syndromes (PDQ®)

Patient Version
Last Modified: 08/19/2011

Dyspnea and Coughing During Advanced Cancer

Key Points for This Section


Many conditions can cause dyspnea.

Dyspnea is the feeling of difficult or uncomfortable breathing or of not getting enough air. It also may be called shortness of breath, breathlessness, or air hunger. In cancer patients, causes of dyspnea include the following:

A diagnosis of the cause of dyspnea or coughing helps to plan treatment.

Diagnostic tests and procedures include the following:

  • Physical exam and history for dyspnea: An exam of the body to check general signs of health, including checking for signs of dyspnea, such as breathing fast or using the neck or chest muscles to breathe. A history of your health habits and past illnesses and treatments will also be taken. Your doctor will also ask about when the dyspnea occurs, what it feels like, other symptoms that happen at the same time as the dyspnea, and anything that makes it better or worse.

  • Functional assessment: An exam to check for how the dyspnea affects your ability to perform activities of daily living such as eating, bathing, or climbing stairs.

  • Chest x-ray: An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.

  • CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.

  • Complete blood count: A procedure in which a sample of blood is taken and checked for the following:

  • Oxygen saturation test: A procedure to check for the amount of oxygen being carried by the red blood cells. A lower than normal amount of oxygen may be a sign of lung disease or other health problems. One method uses a device clipped to the finger. The device senses the amount of oxygen in the blood flowing through the small blood vessels in the finger. Another method uses a sample of blood taken from an artery, usually in the wrist, that is tested for the amount of oxygen.

  • Maximum inspiratory pressure (MIP) test: The MIP is the highest pressure that can be reached in the lungs when you take a deep breath. When you breathe through a device called a manometer, the device measures the pressure. The information is sent to a computer. The pressure level shows how strong the breathing muscles are.

It may be possible to treat the cause of dyspnea.

Treatment may include the following:

  • Radiation therapy: Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. External radiation therapy uses a machine outside the body to send radiation toward the cancer.

  • Hormone therapy: Hormone therapy is a cancer treatment that removes hormones or blocks their action and stops cancer cells from growing. Hormones are substances made by glands in the body and circulated in the bloodstream. Some hormones can cause certain cancers to grow. If tests show that the cancer cells have places where hormones can attach (receptors), drugs, surgery, or radiation therapy is used to reduce the production of hormones or block them from working.

  • Chemotherapy: Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.

  • Laser therapy for tumors inside large airways: Use of a laser beam (a narrow beam of intense light) as a knife to remove the tumor.

  • Cauterization of tumors inside large airways: Use of a hot instrument, an electric current, or a caustic substance to destroy the tumor.

  • Procedures to remove fluid that has built up around the lungs (malignant pleural effusion), around the heart (malignant pericardial effusion), or in the abdominal cavity. (See the sections on controlling the symptoms of malignant pleural effusion 1 and malignant pericardial effusion 2 for more information.)

  • Stent placement: Surgery to place a stent (thin tube) in an airway to keep it open. This may be done if a large airway is blocked by a tumor that is pressing on it from the outside.

  • Medicine:

  • Blood transfusions for anemia.

Treatment of dyspnea depends on the cause of it.

The treatment of dyspnea depends on its cause, as follows:

If the dyspnea is caused by: Then the treatment may be: 
Tumor blocking the large or small airways in the chest or lungRadiation therapy.
Hormone therapy.
Chemotherapy, for tumors that usually respond quickly to this treatment.
Laser surgery to remove the tumor.
Cauterization of tumors.
Pleural effusionRemoval of the extra fluid around the lung using a needle or chest drain.
Pericardial effusionRemoval of the extra fluid around the heart using a needle.
AscitesRemoval of the extra fluid in the abdominal cavity using a needle.
Carcinomatous lymphangitisSteroid therapy.
Chemotherapy, for tumors that usually respond quickly to this treatment.
Superior vena cava syndromeChemotherapy, for tumors that usually respond quickly to this treatment.
Radiation therapy.
Surgery to place a stent in the superior vena cava to keep it open.
Chest infectionsAntibiotics.
Breathing treatments.
Blood clotsAnticoagulants.
Bronchospasms or chronic obstructive pulmonary diseaseBronchodilators.
Inhaled steroids.
Heart failureDiuretics and other heart medicines.
AnemiaBlood transfusion

Treatment may be to control the symptoms of dyspnea.

Treatment to control the symptoms of dyspnea may include the following:

  • Oxygen therapy: Patients who cannot get enough oxygen from the air may be given extra oxygen to inhale from a tank. Devices that concentrate oxygen already in the air may also be prescribed.

  • Medicines: Opioids, such as morphine, may lessen physical and mental distress and exhaustion and the feeling that the patient cannot take enough air in. Other drugs may be used to treat dyspnea that is related to panic disorder or severe anxiety.

  • Supportive care:

Chronic coughing may cause dyspnea.

The causes of chronic coughing are almost the same as the causes of dyspnea. A chronic cough may cause pain, trouble sleeping, dyspnea, and fatigue.

Medicines used to control coughing include the following:

  • Cough-suppressing medicine, including opioids.
  • Medicine that breaks down mucus.
  • An inhaled drug for chronic coughing related to lung cancer.

The cause of the coughing is also treated.



Glossary Terms

abdomen (AB-doh-men)
The area of the body that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
abdominal (ab-DAH-mih-nul)
Having to do with the abdomen, which is the part of the body between the chest and the hips that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
activities of daily living (ak-TIH-vih-teez…DAY-lee LIH-ving)
The tasks of everyday life. These activities include eating, dressing, getting into or out of a bed or chair, taking a bath or shower, and using the toilet. Instrumental activities of daily living are activities related to independent living and include preparing meals, managing money, shopping, doing housework, and using a telephone. Also called ADL.
anemia (uh-NEE-mee-uh)
A condition in which the number of red blood cells is below normal.
antibiotic (AN-tee-by-AH-tik)
A drug used to treat infections caused by bacteria and other microorganisms.
anticoagulant (AN-tee-koh-A-gyuh-lunt)
A substance that is used to prevent and treat blood clots in blood vessels and the heart. Also called blood thinner.
anxiety (ang-ZY-eh-tee)
Feelings of fear, dread, and uneasiness that may occur as a reaction to stress. A person with anxiety may sweat, feel restless and tense, and have a rapid heart beat. Extreme anxiety that happens often over time may be a sign of an anxiety disorder.
artery (AR-tuh-ree)
A blood vessel that carries blood from the heart to tissues and organs in the body.
ascites (uh-SY-teez)
Abnormal buildup of fluid in the abdomen that may cause swelling. In late-stage cancer, tumor cells may be found in the fluid in the abdomen. Ascites also occurs in patients with liver disease.
assessment (uh-SES-ment)
In healthcare, a process used to learn about a patient’s condition. This may include a complete medical history, medical tests, a physical exam, a test of learning skills, tests to find out if the patient is able to carry out the tasks of daily living, a mental health evaluation, and a review of social support and community resources available to the patient.
biofeedback (BY-oh-FEED-bak)
A method of learning to voluntarily control certain body functions such as heartbeat, blood pressure, and muscle tension with the help of a special machine. This method can help control pain.
blood (blud)
A tissue with red blood cells, white blood cells, platelets, and other substances suspended in fluid called plasma. Blood takes oxygen and nutrients to the tissues, and carries away wastes.
blood clot (blud klot)
A mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.
blood transfusion (blud tranz-FYOO-zhun)
A procedure in which a person is given an infusion of whole blood or parts of blood. The blood may be donated by another person, or it may have been taken from the patient earlier and stored until needed. Also called transfusion.
blood vessel (blud VEH-sel)
A tube through which the blood circulates in the body. Blood vessels include a network of arteries, arterioles, capillaries, venules, and veins.
bronchiole (BRONG-kee-ole)
A tiny branch of air tubes in the lungs.
bronchitis (bron-KY-tis)
Inflammation (swelling and reddening) of the bronchi.
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
cauterize (KAW-teh-RIZE)
To destroy tissue using a hot or cold instrument, an electrical current, or a chemical that burns or dissolves the tissue. This process may be used to kill certain types of small tumors or to seal off blood vessels to stop bleeding.
cavity (KA-vih-tee)
A hollow area or hole. It may describe a body cavity (such as the space within the abdomen) or a hole in a tooth caused by decay.
cell (sel)
The individual unit that makes up the tissues of the body. All living things are made up of one or more cells.
cerebrospinal fluid (seh-REE-broh-SPY-nul FLOO-id)
The fluid that flows in and around the hollow spaces of the brain and spinal cord, and between two of the meninges (the thin layers of tissue that cover and protect the brain and spinal cord). Cerebrospinal fluid is made by tissue called the choroid plexus in the ventricles (hollow spaces) in the brain. Also called CSF.
chemotherapy (KEE-moh-THAYR-uh-pee)
Treatment with drugs that kill cancer cells.
chest wall (chest wawl)
The muscles, bones, and joints that make up the area of the body between the neck and the abdomen.
chest x-ray (chest EX-ray)
An x-ray of the structures inside the chest. An x-ray is a type of high-energy radiation that can go through the body and onto film, making pictures of areas inside the chest, which can be used to diagnose disease.
chronic (KRAH-nik)
A disease or condition that persists or progresses over a long period of time.
chronic obstructive pulmonary disease (KRAH-nik ub-STRUK-tiv PUL-muh-NAYR-ee dih-ZEEZ)
A type of lung disease marked by permanent damage to tissues in the lungs, making it hard to breathe. Chronic obstructive pulmonary disease includes chronic bronchitis, in which the bronchi (large air passages) are inflamed and scarred, and emphysema, in which the alveoli (tiny air sacs) are damaged. It develops over many years and is usually caused by cigarette smoking. Also called COPD.
complete blood count (kum-PLEET blud kownt)
A test to check the number of red blood cells, white blood cells, and platelets in a sample of blood. Also called blood cell count and CBC.
congestive heart failure (kun-JES-tiv hart FAYL-yer)
Weakness of the heart muscle that leads to a buildup of fluid in body tissues.
CT scan (… skan)
A series of detailed pictures of areas inside the body taken from different angles. The pictures are created by a computer linked to an x-ray machine. Also called CAT scan, computed tomography scan, computerized axial tomography scan, and computerized tomography.
device (dee-VISE)
An object that has a specific use. In medicine, wheelchairs, pumps, and artificial limbs are examples of devices.
diagnostic procedure (DY-ug-NAH-stik proh-SEE-jer)
A type of test used to help diagnose a disease or condition. Mammograms and colonoscopies are examples of diagnostic procedures. Also called diagnostic test.
diaphragm (DY-uh-fram)
The thin muscle below the lungs and heart that separates the chest from the abdomen.
disorder (dis-OR-der)
In medicine, a disturbance of normal functioning of the mind or body. Disorders may be caused by genetic factors, disease, or trauma.
distress (dih-STRESS)
Extreme mental or physical pain or suffering.
diuretic (DY-yuh-REH-tik)
A drug that increases the production of urine.
drug (drug)
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.
dyspnea (DISP-nee-uh)
Difficult, painful breathing or shortness of breath.
emphysema (EMP-fuh-ZEE-muh)
Pulmonary emphysema is a disorder affecting the alveoli (tiny air sacs) of the lungs. The transfer of oxygen and carbon dioxide in the lungs takes place in the walls of the alveoli. In emphysema, the alveoli become abnormally inflated, damaging their walls and making it harder to breathe. People who smoke or have chronic bronchitis have an increased risk of emphysema.
external radiation therapy (...RAY-dee-AY-shun THAYR-uh-pee)
A type of radiation therapy that uses a machine to aim high-energy rays at the cancer from outside of the body. Also called external-beam radiation therapy.
fatigue (fuh-TEEG)
A condition marked by extreme tiredness and inability to function due lack of energy. Fatigue may be acute or chronic.
fluid (FLOO-id)
A substance that flows smoothly and takes the shape of its container. Liquids and gases are fluids.
gland (gland)
An organ that makes one or more substances, such as hormones, digestive juices, sweat, tears, saliva, or milk. Endocrine glands release the substances directly into the bloodstream. Exocrine glands release the substances into a duct or opening to the inside or outside of the body.
hemoglobin (HEE-moh-GLOH-bin)
The substance inside red blood cells that binds to oxygen in the lungs and carries it to the tissues.
hormone (HOR-mone)
One of many chemicals made by glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or organs. Some hormones can also be made in the laboratory.
hormone therapy (HOR-mone THAYR-uh-pee)
Treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body’s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called endocrine therapy, hormonal therapy, and hormone treatment.
infection (in-FEK-shun)
Invasion and multiplication of germs in the body. Infections can occur in any part of the body and can spread throughout the body. The germs may be bacteria, viruses, yeast, or fungi. They can cause a fever and other problems, depending on where the infection occurs. When the body’s natural defense system is strong, it can often fight the germs and prevent infection. Some cancer treatments can weaken the natural defense system.
inflammation (IN-fluh-MAY-shun)
Redness, swelling, pain, and/or a feeling of heat in an area of the body. This is a protective reaction to injury, disease, or irritation of the tissues.
inhalation (IN-huh-LAY-shun)
In medicine, refers to the act of taking a substance into the body by breathing.
injection (in-JEK-shun)
Use of a syringe and needle to push fluids or drugs into the body; often called a "shot."
laser (LAY-zer)
A device that forms light into intense, narrow beams that may be used to cut or destroy tissue, such as cancer tissue. It may also be used to reduce lymphedema (swelling caused by a buildup of lymph fluid in tissue) after breast cancer surgery. Lasers are used in microsurgery, photodynamic therapy, and many other procedures to diagnose and treat disease.
laser therapy (LAY-zer THAYR-uh-pee)
Treatment that uses intense, narrow beams of light to cut and destroy tissue, such as cancer tissue. Laser therapy may also be used to reduce lymphedema (swelling caused by a buildup of lymph fluid in tissue) after breast cancer surgery.
lung (lung)
One of a pair of organs in the chest that supplies the body with oxygen, and removes carbon dioxide from the body.
lung cancer (lung KAN-ser)
Cancer that forms in tissues of the lung, usually in the cells lining air passages. The two main types are small cell lung cancer and non-small cell lung cancer. These types are diagnosed based on how the cells look under a microscope.
lymph vessel (limf ...)
A thin tube that carries lymph (lymphatic fluid) and white blood cells through the lymphatic system. Also called lymphatic vessel.
malignant (muh-LIG-nunt)
Cancerous. Malignant cells can invade and destroy nearby tissue and spread to other parts of the body.
malignant pleural effusion (muh-LIG-nunt PLOOR-ul eh-FYOO-zhun)
A condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue (pleura) lining the outside of the lung and the wall of the chest cavity. Lung cancer, breast cancer, lymphoma, and leukemia cause most malignant pleural effusions.
maximum inspiratory pressure test (MAK-sih-mum in-SPY-ruh-TOR-ee PREH-sher…)
A test that measures the strength of the muscles used in breathing. A person inhales and exhales through a device called a manometer, and the pressures are recorded by a computer. Also called MIP test.
medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
mucus (MYOO-kus)
A thick, slippery fluid made by the membranes that line certain organs of the body, including the nose, mouth, throat, and vagina.
opioid (OH-pee-OYD)
A substance used to treat moderate to severe pain. Opioids are like opiates, such as morphine and codeine, but are not made from opium. Opioids bind to opioid receptors in the central nervous system. Opioids used to be called narcotics. An opioid is a type of alkaloid.
organ (OR-gun)
A part of the body that performs a specific function. For example, the heart is an organ.
oxygen (OK-sih-jen)
A colorless, odorless gas. It is needed for animal and plant life. Oxygen that is breathed in enters the blood from the lungs and travels to the tissues.
oxygen saturation test (OK-sih-jen SA-chuh-RAY-shun…)
A test that measures the amount of oxygen being carried by red blood cells. One method uses a device that shines light through a finger. The device measures the amount of oxygen in the blood based on the way red blood cells carrying oxygen absorb and reflect light. In another method blood is taken from an artery and the amount of oxygen is measured directly. An oxygen level that is lower than normal may be a sign of lung disease or other medical conditions.
oxygen therapy (OK-sih-jen THAYR-uh-pee)
Treatment in which a storage tank of oxygen or a machine called a compressor is used to give oxygen to people with breathing problems. It may be given through a nose tube, a mask, or a tent. The extra oxygen is breathed in along with normal air. Also called supplemental oxygen therapy.
panic (PA-nik)
Sudden extreme anxiety or fear that may cause irrational thoughts or actions. Panic may include rapid heart rate, flushing (a hot, red face), sweating, and trouble breathing.
paralysis (puh-RA-lih-sis)
Loss of ability to move all or part of the body.
pericardial effusion (PAYR-ih-KAR-dee-ul eh-FYOO-zhun)
An abnormal collection of fluid inside the sac that covers the heart.
physical examination (FIH-zih-kul eg-ZA-mih-NAY-shun)
An exam of the body to check for general signs of disease.
physical therapy (FIH-zih-kul THAYR-uh-pee)
The use of exercises and physical activities to help condition muscles and restore strength and movement. For example, physical therapy can be used to restore arm and shoulder movement and build back strength after breast cancer surgery.
platelet (PLAYT-let)
A tiny piece of a cell found in the blood that breaks off from a large cell found in the bone marrow. Platelets help wounds heal and prevent bleeding by forming blood clots. Also called thrombocyte.
pleural effusion (PLOOR-ul eh-FYOO-zhun)
An abnormal collection of fluid between the thin layers of tissue (pleura) lining the lung and the wall of the chest cavity.
pneumonia (noo-MOH-nyuh)
A severe inflammation of the lungs in which the alveoli (tiny air sacs) are filled with fluid. This may cause a decrease in the amount of oxygen that blood can absorb from air breathed into the lung. Pneumonia is usually caused by infection but may also be caused by radiation therapy, allergy, or irritation of lung tissue by inhaled substances. It may involve part or all of the lungs.
prescription (prih-SKRIP-shun)
A doctor's order for medicine or another intervention.
protein (PROH-teen)
A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies.
radiation therapy (RAY-dee-AY-shun THAYR-uh-pee)
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiotherapy.
receptor (reh-SEP-ter)
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.
red blood cell (red blud sel)
A cell that carries oxygen to all parts of the body. Also called erythrocyte and RBC.
regional chemotherapy (REE-juh-nul KEE-moh-THAYR-uh-pee)
Treatment with anticancer drugs directed to a specific area of the body.
relaxation technique (ree-lak-SAY-shun tek-NEEK)
A method used to help reduce muscle tension and stress, lower blood pressure, and control pain. Examples of relaxation techniques include tensing and relaxing muscles throughout the body, guided imagery (focusing the mind on positive images), meditation (focusing thoughts), and deep breathing exercises.
spasm (SPA-zum)
A sudden contraction of a muscle or group of muscles, such as a cramp.
stage (stayj)
The extent of a cancer in the body. Staging is usually based on the size of the tumor, whether lymph nodes contain cancer, and whether the cancer has spread from the original site to other parts of the body.
stent (stent)
A device placed in a body structure (such as a blood vessel or the gastrointestinal tract) to keep the structure open.
steroid drug (STAYR-oyd ...)
A type of drug used to relieve swelling and inflammation. Some steroid drugs may also have antitumor effects.
supportive care (suh-POR-tiv kayr)
Care given to improve the quality of life of patients who have a serious or life-threatening disease. The goal of supportive care is to prevent or treat as early as possible the symptoms of a disease, side effects caused by treatment of a disease, and psychological, social, and spiritual problems related to a disease or its treatment. Also called comfort care, palliative care, and symptom management.
surgery (SER-juh-ree)
A procedure to remove or repair a part of the body or to find out whether disease is present. An operation.
symptom (SIMP-tum)
An indication that a person has a condition or disease. Some examples of symptoms are headache, fever, fatigue, nausea, vomiting, and pain.
systemic chemotherapy (sis-TEH-mik KEE-moh-THAYR-uh-pee)
Treatment with anticancer drugs that travel through the blood to cells all over the body.
talk therapy (...THAYR-uh-pee)
Treatment of mental, emotional, personality, and behavioral disorders using methods such as discussion, listening, and counseling. Also called psychotherapy.
tissue (TIH-shoo)
A group or layer of cells that work together to perform a specific function.
tumor (TOO-mer)
An abnormal mass of tissue that results when cells divide more than they should or do not die when they should. Tumors may be benign (not cancer), or malignant (cancer). Also called neoplasm.
vein (vayn)
A blood vessel that carries blood to the heart from tissues and organs in the body.
white blood cell (hwite blud sel)
A type of immune cell. Most white blood cells are made in the bone marrow and are found in the blood and lymph tissue. White blood cells help the body fight infections and other diseases. Granulocytes, monocytes, and lymphocytes are white blood cells. Also called leukocyte and WBC.
x-ray (EX-ray)
A type of radiation used in the diagnosis and treatment of cancer and other diseases. In low doses, x-rays are used to diagnose diseases by making pictures of the inside of the body. In high doses, x-rays are used to treat cancer.

Table of Links

1http://www.cancer.gov/cancertopics/pdq/supportivecare/cardiopulmonary/Patient/P
age3#Section_210
2http://www.cancer.gov/cancertopics/pdq/supportivecare/cardiopulmonary/Patient/P
age4#Section_132
3http://www.cancer.gov/cancertopics/pdq/supportivecare/cardiopulmonary/Patient/T
able1