The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Acute/Delayed Emesis Etiology

Added text on the incidence of chemotherapy-induced nausea and vomiting in ten community oncology clinics (cited Cohen et al. as reference 2).

Prevention of Acute/Delayed Emesis

Added substance P antagonists (NK-1 receptor antagonists), benzodiazepines, and olanzapine as groups of drugs with proven antiemetic activity.

Added text on pediatric doses of prochlorperazine.

Added text to state that tropisetron, while not approved by the U.S. Food and Drug Administration, is available internationally.

Updated the subsection on Management of Chemotherapy-induced Nausea and Vomiting.

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