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Pruritus (PDQ®)     
Last Modified: 01/21/2009
Patient Version
Treatment

Maintaining healthy skin may relieve pruritus. Good skin care includes adequate nutrition and daily fluid intake, protection from the environment, and cleansing practices that don't dry the skin.

Some specific factors that may relieve itching are the following:

  • Moisturizing creams and lotions. These water-containing products form films over the skin surface and encourage the production of moisture beneath the film. This prevents dryness, which can cause itching. These products should be carefully chosen for each person's needs. Some ingredients, such as petrolatum, lanolin, and mineral oil can cause allergic reactions in some people.


  • Powders, bubble baths, and cornstarch. These products should be used with caution because they can irritate the skin and cause itching. Cornstarch is an effective treatment for itching that is associated with dry skin due to radiation therapy but should not be applied to moist surfaces, to areas with hair, sweat glands, skin folds, or to areas close to mucosal surfaces, such as the vagina or rectum. When cornstarch becomes moist, it can promote fungal growth. Some powders, such as those that contain talcum and aluminum, can cause skin irritation during radiation therapy and should be avoided when you are receiving radiation treatment. Alcohol or menthol, which are found in some creams and over-the-counter lotions, may also produce skin reactions. Topical steroid creams may reduce itching but may cause thinning of the skin and can make it more prone to injury.


  • Tepid baths. Baths that are moderately warm and last no longer than one half hour every day or every two days can help relieve itching. Frequent bathing can aggravate dry skin, and hot baths can promote itching.


  • Mild soaps. Mild soaps contain less soap or detergent that can irritate skin. Oil can be added to the water at the end of a bath or applied to the skin before drying.


  • A cool humid environment. Heat can cause itching. Your skin loses moisture when the humidity is low. A cool, humid environment may prevent your skin from itching.


  • Removal of detergent residue. Residue left on clothing by detergent and fabric softeners may aggravate pruritus. The irritation can be reduced by adding vinegar (one teaspoon per quart of water) to the laundry rinse cycle or by using a mild laundry soap that is sold for washing baby clothes.


  • Cotton clothing and bed sheets. Body heat, wool, and some synthetic fabrics can aggravate itching. It may be helpful to wear loose-fitting, lightweight cotton clothing and to use cotton bed sheets.


In addition to the skin-care factors, medications applied to the skin or taken by mouth may be necessary to treat pruritus. Antibiotics may relieve itching caused by infection. Antihistamines may be useful in some cases of pruritus. Sedatives, tranquilizers, and antidepressants may be useful treatments. Aspirin seems to have reduced itching in some patients but increases it for others. Aspirin combined with cimetidine may be effective for patients with Hodgkin lymphoma or polycythemia vera.

Interrupting the itch-scratch-itch cycle, an increase in itching that can result from the process of scratching, may also help to alleviate pruritus. The cycle may be broken by applying a cool washcloth or ice over the affected area. Rubbing the skin and applying pressure or vibration to the skin may also help. Other methods that may be useful in relieving symptoms include distraction, music therapy, relaxation, and imagery techniques.



Glossary Terms

alcohol (AL-kuh-hol)
A chemical substance found in beer, wine, and liquor. Alcohol is also found in some medicines, mouthwashes, essential oils (scented liquid taken from plants), and household products.
allergic response (uh-LER-jik reh-SPONTS)
A hypersensitive immune reaction to a substance that normally is harmless or would not cause an immune response in most people. An allergic response may cause harmful symptoms such as itching or inflammation or tissue injury.
antibiotic (AN-tee-by-AH-tik)
A drug used to treat infections caused by bacteria and other microorganisms.
antidepressant (AN-tee-dee-PREH-sunt)
A drug used to treat depression.
antihistamine (AN-tee-HIS-tuh-meen)
A type of drug that blocks the action of histamines, which can cause fever, itching, sneezing, a runny nose, and watery eyes. Antihistamines are used to prevent fevers in patients receiving blood transfusions and to treat allergies, coughs, and colds.
aspirin
A drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention.
cimetidine
A drug usually used to treat stomach ulcers and heartburn. It is also commonly used in a regimen to prevent allergic reactions.
distraction
In medicine, a pain relief method that takes the patient's attention away from the pain.
fluid (FLOO-id)
A substance that flows smoothly and takes the shape of its container. Liquids and gases are fluids.
fungus (FUN-gus)
A plant-like organism that does not make chlorophyll. Mushrooms, yeasts, and molds are examples. The plural is fungi.
gland
An organ that makes one or more substances, such as hormones, digestive juices, sweat, tears, saliva, or milk. Endocrine glands release the substances directly into the bloodstream. Exocrine glands release the substances into a duct or opening to the inside or outside of the body.
Hodgkin lymphoma (HOJ-kin lim-FOH-muh)
A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin disease.
imagery (IH-mij-ree)
A technique in which the person focuses on positive images in his or her mind.
infection
Invasion and multiplication of germs in the body. Infections can occur in any part of the body and can spread throughout the body. The germs may be bacteria, viruses, yeast, or fungi. They can cause a fever and other problems, depending on where the infection occurs. When the body’s natural defense system is strong, it can often fight the germs and prevent infection. Some cancer treatments can weaken the natural defense system.
lanolin (LA-noh-lin)
An oily substance taken from sheep's wool. Lanolin is used in moisturizing creams and lotions to treat dry, itchy skin.
medication (MEH-dih-KAY-shun)
A legal drug that is used to prevent, treat, or relieve symptoms of a disease or abnormal condition.
mineral oil (MIH-neh-rul OYL)
A type of oil that is made from petroleum (mixture of oily liquids found in the earth). Mineral oil is used in laxatives, lubricants, creams, and lotions.
mucosa (myoo-KOH-suh)
The moist, inner lining of some organs and body cavities (such as the nose, mouth, lungs, and stomach). Glands in the mucosa make mucus (a thick, slippery fluid). Also called mucous membrane.
nutrition (noo-TRIH-shun)
The taking in and use of food and other nourishing material by the body. Nutrition is a 3-part process. First, food or drink is consumed. Second, the body breaks down the food or drink into nutrients. Third, the nutrients travel through the bloodstream to different parts of the body where they are used as "fuel" and for many other purposes. To give the body proper nutrition, a person has to eat and drink enough of the foods that contain key nutrients.
over-the-counter
A medicine that can be bought without a prescription (doctor's order). Examples include analgesics (pain relievers) such as aspirin and acetaminophen. Also called nonprescription and OTC.
petrolatum (PEH-troh-LAY-tum)
A thick, greasy, substance with no odor or taste made from petroleum (mixture of oily liquids found in the earth). Petrolatum is used on the skin to prevent drying and to help heal scrapes and burns. It is also used as a base for some ointments. Also called petroleum jelly.
polycythemia vera (PAH-lee-sy-THEE-mee-uh VAYR-uh)
A disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to thicken. The number of white blood cells and platelets may also increase. The extra blood cells may collect in the spleen and cause it to become enlarged. They may also cause bleeding problems and make clots form in blood vessels.
pruritus (proo-RY-tus)
Itching. Severe itching may be a side effect of some cancer treatments and a symptom of some types of cancers.
radiation therapy (RAY-dee-AY-shun THAYR-uh-pee)
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiotherapy.
rectum (REK-tum)
The last several inches of the large intestine closest to the anus.
relaxation technique
A method used to reduce tension and anxiety, and control pain.
sedative (SEH-duh-tiv)
A drug or substance used to calm a person down, relieve anxiety, or help a person sleep.
steroid cream (STAYR-oyd...)
A skin cream containing a type of drug that relieves swelling, itching, and inflammation.
symptom
An indication that a person has a condition or disease. Some examples of symptoms are headache, fever, fatigue, nausea, vomiting, and pain.
synthetic (sin-THEH-tik)
Having to do with substances that are man-made instead of taken from nature.
talc
A mineral, usually used in a powdered form. In cancer treatment, sterile talc is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall). Talc is inserted into the space, causing it to close up, so fluid cannot collect there. Also called sterile talc powder.
topical
On the surface of the body.
vagina (vuh-JY-nuh)
The muscular canal extending from the uterus to the exterior of the body. Also called birth canal.