Table 3. Outcome According to Treatment Protocol for Adolescents and Young Adults with ALL
| Site and Study Group | Adolescent and Young Adult Patients (No.) | Median age (y) | Survival (%) |
| United States [29] | |||
| CCG (Pediatric) | 197 | 16 | 67, OS 7 y |
| CALGB (Adult) | 124 | 19 | 46 |
| France [35] | |||
| FRALLE 93 (Pediatric) | 77 | 16 | 67 EFS |
| LALA 94 | 100 | 18 | 41 |
| Italy [42] | |||
| AEIOP (Pediatric) | 150 | 15 | 80, OS 2 y |
| GIMEMA (Adult) | 95 | 16 | 71 |
| Netherlands [43] | |||
| DCOG (Pediatric) | 47 | 12 | 71 EFS |
| HOVON | 44 | 20 | 38 |
| Sweden [44] | |||
| NOPHO 92 (Pediatric) | 36 | 16 | 74, OS 5 y |
| Adult ALL | 99 | 18 | 39 |
| United Kingdom [31] | |||
| MRC ALL (Pediatric) | 61 | 15–17 | 71, OS 5 y |
| UKALL XII (Adult) | 67 | 15–17 | 56 |
| ALL = acute lymphoblastic leukemia; EFS = event-free survival; OS = overall survival. | |||
| AEIOP = Associazione Italiana Ematologia Oncologia Pediatrica; CALGB = Cancer and Leukemia Group B; CCG = Children's Cancer Group; DCOG = Dutch Childhood Oncology Group; FRALLE = French Acute Lymphoblastic Leukaemia; GIMEMA = Gruppo Italiano Malattie e Matologiche dell'Adulto; HOVON = Dutch-Belgian Hemato-Oncology Cooperative Group; LALA = France-Belgium Group for Lymphoblastic Acute Leukemia in Adults; MRC = Medical Research Council (United Kingdom); NOPHO = Nordic Society for Pediatric Hematology and Oncology; UKALL = United Kingdom Acute Lymphoblastic Leukaemia. |
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