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Childhood Hodgkin Lymphoma Treatment (PDQ®)

Health Professional Version
Last Modified: 04/08/2014

Changes to This Summary (04/08/2014)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information

Added text to state that a family history of Hodgkin lymphoma in siblings or parents has been associated with an increased risk of this disease (cited Crump et al. as reference 11).

Added Ilivitzki et al. as reference 34.

Diagnosis and Staging

Added Haase et al. as reference 3.

Added text to state that a report of 38 patients compared bone marrow involvement diagnosed by biopsy with bone marrow involvement assessed by PET scan positivity; the report showed that the sensitivity of PET was 87.5% and the negative predictive value of PET was 96% for bone marrow involvement (cited Agrawal et al. as reference 12).

Added Cheng et al. as reference 13.

Added text to state that the concept of reduced frequency of imaging has been supported by other investigations (cited Hartridge-Lambert et al. and Friedmann et al. as references 36 and 37, respectively).

Treatment for Newly Diagnosed Children and Adolescents with Hodgkin Lymphoma

Added Maraldo et al. as reference 30.

Revised Table 3 to update the radiation field definitions (cited Terezakis et al. as reference 31).

Treatment of Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents

Added Rancea et al. as reference 16.

Late Effects from Childhood/Adolescent Hodgkin Lymphoma Therapy

Added Koontz et al. and Schellong et al. as references 46 and 47, respectively.

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.