Stage III Esophageal Cancer

Current Clinical Trials

Standard treatment options:

1. Surgical resection of T3 lesions.
2. Chemoradiation.

Treatment options under clinical evaluation:

• Chemoradiation with subsequent surgery, such as in the RTOG-8501 trial, which is now closed.[1,2]

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III esophageal cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References

1. Cooper JS, Guo MD, Herskovic A, et al.: Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. JAMA 281 (17): 1623-7, 1999.  [PUBMED Abstract]
   
   
2. Herskovic A, Al-Sarraf M: Combination of 5-Fluorouracil and Radiation in Esophageal Cancer. Semin Radiat Oncol 7 (4): 283-290, 1997.  [PUBMED Abstract]