Centers of Cancer Nanotechnology Excellence (CCNEs)
The multi-disciplinary CCNE teams are the main venue for the discovery and tool development toward the application of nanotechnology to clinical oncology. Teams are focused on integrated technology solutions and the aggressive development of these solutions from pre-clinical to clinical application. These are multiple project centers and are designed to enable multi-disciplinary team research by linking physical scientists, engineers and technologists working at the nanoscale with cancer biologists and oncologists specializing in the diagnosis, prevention and treatment of cancer.
Designs and develops nanotherapies and nanotech tools to guide selection of combination cancer immunotherapy and targeted therapy treatments for brain cancers and melanoma.
Focuses on the design, synthesis, characterization, and development of spherical nucleic acid constructs as effective nanotherapeutic, single-entity agents for the treatment of glioblastoma multiforme and prostate cancers.
Sloan Kettering and Cornell University — MSKCC-Cornell Center for Translation of Cancer Nanomedicine
Advancment and translation of a suite of ultrasmall (<10 nm) fluorescent silica organic hybrid nanoparticles, Cornell dots, with tunable size, brightness, and geometry that will dramatically impact diagnosis and treatment of melanoma and more.
Stanford University — Center of Cancer Nanotechnology Excellence for Translational Diagnostics (CCNE-TD)
The overarching focus is to develop and utilize in vitro nanosensors and in vivo molecular imaging tools to advance methods in earlier detection of aggressive cancers as well as monitoring response to therapy for both prostate and lung cancers.
University of North Carolina, Chapel Hill — Nano Approaches to Modulate Host Cell Response for Cancer Therapy
Will exploit host responses by way of nanoscale approaches for disease management and treatment of melanoma and lung cancer.
Will enable MM treatment outcomes with minimal off-target toxicity by developing novel nanotherapeutics that combine unique drug delivery mechanisms with spatiotemporal treatment paradigms.