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  • Posted: 11/13/2006
  • Updated: 04/11/2014

Table 11. Online Gene Mutation Prediction Programs

Resource Description 
HuGE = Human Genome Epidemiology; MMR = mismatch repair; MRC = Medical Research Council.
HuGE Risk Translator Calculates the predictive value of genetic markers.
MRC Human Genetics Unit, Edinburgh Predicts the likelihood of mutations in one of the MMR genes in persons with colon cancer.
The Penn II Risk Model Estimates the probability that an individual has a BRCA1 or BRCA2 mutation.
PREMM1,2,6 Model: Prediction Model for MLH1, MSH2, and MSH6 Gene Mutations Estimates the probability that an individual carries a mutation in one of the MMR genes.