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PDQ® Cancer Information Summaries: Genetics

Cancer Genetics Overview (PDQ®) – health professional
Includes information about genetic counseling, familial cancer susceptibility syndromes, clinical sequencing, and genetics resources.

Cancer Genetics Risk Assessment and Counseling (PDQ®) – health professional
Includes the components of cancer genetics risk assessment and counseling, genetic testing considerations, psychosocial assessments, and the ethical, legal, and social implications of genetic testing.

Genetics of Breast and Gynecologic Cancers (PDQ®) – health professional
Includes BRCA1/BRCA2, Lynch syndrome, PALB2, Li-Fraumeni syndrome, hereditary diffuse gastric cancer, moderate risk genes, and other genes/syndromes.

Genetics of Colorectal Cancer (PDQ®) – health professional
Includes Lynch syndrome, familial adenomatous polyposis, MUTYH-associated polyposis, and other genes/syndromes.

Genetics of Endocrine and Neuroendocrine Neoplasias (PDQ®) – health professional
Includes multiple endocrine neoplasia type 1 (MEN1), MEN2, MEN4, familial pheochromocytoma and paraganglioma syndrome, Carney-Stratakis syndrome, and familial nonmedullary thyroid cancer.

Genetics of Gastric Cancer (PDQ®) – health professional
Includes hereditary diffuse gastric cancer (CDH1 and CTNNA1 genes) and other syndromes.

Genetics of Renal Cell Carcinoma (Kidney Cancer) (PDQ®) – health professional
Genetics of Kidney Cancer (PDQ®) – patient version 
Includes Von-Hippel Lindau Disease, Hereditary Leiomyomatosis and Renal Cell Cancer, Hereditary Papillary Renal Carcinoma, and Birt-Hogg-Dubé Syndrome.

Genetics of Prostate Cancer (PDQ®) – health professional
Includes BRCA1/BRCA2, HOXB13, Lynch syndrome, ATM and CHEK2.

Genetics of Skin Cancer (PDQ®) – health professional
Includes several genes and hereditary syndromes associated with:

  • Basal cell carcinoma, such as basal cell nevus syndrome and xeroderma pigmentosum
  • Squamous cell carcinoma, such as epidermolysis bullosa and Fanconi anemia
  • Melanoma, such as CDKN2A, MITF, and BAP1