Treatment Options for Intraocular (Eye) Melanoma
Iris Melanoma
Ciliary Body Melanoma
Small Choroid Melanoma
Medium and Large Choroid Melanoma
Extraocular Extension Melanoma and Metastatic Intraocular (Eye) Melanoma
Recurrent Intraocular (Eye) Melanoma
A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.
Iris MelanomaTreatment of iris melanoma may include the following:
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with iris melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Ciliary Body MelanomaTreatment of tumors in the ciliary body and choroid may include the following:
- Plaque radiation therapy.
- Charged-particle external radiation therapy.
- Surgery (local tumor resection or enucleation).
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Small Choroid MelanomaTreatment of small choroid melanoma may include the following:
- Watchful waiting.
- Plaque radiation therapy.
- Charged-particle external radiation therapy.
- Gamma Knife radiation surgery.
- Photocoagulation.
- Thermotherapy.
- Surgery (local tumor resection or enucleation).
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Medium and Large Choroid MelanomaTreatment of medium choroid melanoma may include the following:
- Plaque radiation therapy.
- Plaque radiation therapy with photocoagulation or thermotherapy.
- Charged-particle external radiation therapy.
- Surgery (local tumor resection or enucleation).
Treatment of large choroid melanoma may include surgery (enucleation) with or without radiation therapy before surgery.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, medium/large size. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Extraocular Extension Melanoma and Metastatic Intraocular (Eye) MelanomaTreatment of extraocular extension melanoma or metastatic melanoma may include surgery (exenteration) with or without radiation therapy.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with extraocular extension melanoma and metastatic intraocular melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Recurrent Intraocular (Eye) MelanomaTreatment of recurrent intraocular melanoma is usually within a clinical trial.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent intraocular melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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