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Intraocular (Uveal) Melanoma Treatment (PDQ®)

Patient Version
Last Modified: 04/25/2014

Treatment Options for Intraocular (Uveal) Melanoma

Iris Melanoma
Ciliary Body Melanoma
Choroid Melanoma
Extraocular Extension Melanoma and Metastatic Intraocular (Uveal) Melanoma
Recurrent Intraocular (Uveal) Melanoma



Iris Melanoma

Treatment of iris melanoma may include the following:

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with iris melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Ciliary Body Melanoma

Treatment of tumors in the ciliary body and choroid may include the following:

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Choroid Melanoma

Treatment of small choroid melanoma may include the following:

Treatment of medium choroid melanoma may include the following:

  • Plaque radiation therapy with or without photocoagulation or thermotherapy.
  • Charged-particle external-beam radiation therapy.
  • Surgery (resection or enucleation).

Treatment of large choroid melanoma may include the following:

  • Enucleation when the tumor is too large for treatments that save the eye.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ciliary body and choroid melanoma, small size. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Extraocular Extension Melanoma and Metastatic Intraocular (Uveal) Melanoma

Treatment of extraocular extension melanoma that has spread to the bone around the eye may include the following:

An effective treatment for metastatic intraocular melanoma has not been found. A clinical trial may be a treatment option. Talk with your doctor about your treatment options.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with extraocular extension melanoma and metastatic intraocular melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Recurrent Intraocular (Uveal) Melanoma

An effective treatment for recurrent intraocular melanoma has not been found. A clinical trial may be a treatment option. Talk with your doctor about your treatment options.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent intraocular melanoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.