This research trial studies the health related quality of life in patients with colorectal cancer that has spread to the liver (metastatic) who are undergoing liver surgery. Collecting information from quality of life questionnaires from patients before and after liver surgery may help doctors understand the long-term effects that cancer treatments have on patients and may help patients to make better decisions about their treatment options and know what to expect after surgery.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT02399995.
PRIMARY OBJECTIVE:
I. To assess health related quality of life (HRQoL) using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), Quality of Life Questionnaire Liver Metastases Colorectal 21 (QLQ-LMC21) and the European Quality of Life (EuroQoL) Five Dimension Five Level Scale (EQ-5D-5L)/visual analogue scale (VAS), in patients at high risk of recurrence undergoing hepatectomy for colorectal cancer liver metastasis (CRLM) and to evaluate global and disease specific changes over time.
SECONDARY OBJECTIVE:
I. To explore how HRQoL scores are impacted as patients transition through different stages in the course of disease and treatment during follow up, including: disease free off treatment, recurrent disease salvageable with surgery, recurrent disease not salvageable with surgery, persistent disease on long term non-curative therapies, and/or best supportive care.
OUTLINE:
Patients complete quality of life questionnaires at baseline, at the first postoperative clinic visit, and at 6, 12, 18, 24, and 36 months after hepatectomy.
Trial PhaseNo phase specified
Trial TypeNot provided by clinicaltrials.gov
Lead OrganizationMemorial Sloan Kettering Cancer Center
Principal InvestigatorMichael D'Angelica
