3RP-AYA Intervention in Reducing Stress and Promoting Stress Management in Adolescent and Young Adult Cancer Survivors
This trial studies the feasibility and acceptability of Relaxation Response Resiliency Program for adolescent and young adult (3RP-AYA) intervention in reducing stress and promoting stress management in adolescent and young adult who have completed treatment for cancer within the past five years. 3RP-AYA intervention uses a variety of mind-body approaches, such as imagery, relaxation, and yoga that may buffer stress and promote psychological resiliency and physical well-being in adolescent and young adult cancer survivors.
- Diagnosed with any cancer between ages 15 and 27
- Completed cancer treatment within the past 5 years
- Unwilling or unable to participate in the study
- Unable to speak or read English
- Is medically or otherwise unable to participate (as determined by a physician or study principal investigator [PI])
- Unwilling or unable to participate in study sessions delivered via the Partners Telehealth videoconferencing software
- Participation in a focus group during phase 1 (DF/HCC 17-315) or the sister-protocol (DF/HCC 17-063)
Locations & Contacts
Trial Objectives and Outline
I. To examine, in a pilot randomized controlled trial (RCT) (total n=72, goal of having approximately n=60 completers), the feasibility and acceptability of an 8-session stress-management and resiliency group program (3RP-AYA) delivered via videoconference technology for survivors of AYA cancer between the ages of 16-29 at study enrollment, but who were diagnosed between ages 15 and 27 and who are within 5 years of treatment completion.
I. Examine the preliminary effects of the 3RP-AYA on stress and stress management among AYAs.
II. Examine the preliminary effects of the 3RP-AYA on psychosocial measures of mindfulness, depressed mood, anxiety and stress collected at three timepoints: T0 (baseline), T1 (immediate start resiliency intervention group [IG]: posttreatment, waitlist control group [WG]: baseline), T2 (IG: 3 month follow-up, WG: posttreatment).
III. Explore the feasibility and acceptability of collecting hair samples to examine intervention-related changes in cortisol, a stress biomarker.
IV. Examine AYA reasons for deciding not to participate in this behavioral trial.
OUTLINE: Patients are randomized to 1 of 2 groups.
GROUP I: Patients receive 3RP-AYA intervention consisting of a group session once weekly over 90 minutes each for 8 weeks.
GROUP II: Patients receive 3RP-AYA intervention consisting of a group session once weekly over 90 minutes each for 8 weeks after 3 months.
After completion of study program, patients are followed up at 3 months.
Trial Phase & Type
No phase specified
Dana-Farber Harvard Cancer Center
Secondary IDs NCI-2018-03786
Clinicaltrials.gov ID NCT03768336