This pilot trial studies how well inhaled essential oils work in improving side effects in patients who are undergoing cancer treatment such as chemotherapy, targeted therapy, and/or immunotherapy given through the vein (intravenously). Aromatherapy using essential oils, such as ginger essential oil, German chamomile essential oil, and bergamot essential oil, may improve side effects such as nausea, anxiety, appetite, and fatigue in patients undergoing treatment for cancer.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT03858855.
PRIMARY OBJECTIVES:
I. To determine if aromatherapy, specifically inhaled essential oil, is beneficial for side effects related to cancer treatments involving chemotherapy, targeted therapy, and/or immunotherapy administered intravenously.
II. To describe the effect of inhaled ginger essential oil, German chamomile essential oil, and bergamot essential oil on nausea and anxiety of patients receiving chemotherapy, targeted therapy, and/or immunotherapy administered intravenously.
III. To describe the effect of decreased levels of nausea and/or anxiety on levels of appetite and/or fatigue.
IV. To evaluate the acceptability of using a personal inhalation bottle for inhalation of essential oils.
OUTLINE: Patients are randomized to 1 of 4 groups.
GROUP I: Patients inhale 7 drops of bergamot essential oil using an essential oil administration bottle three times daily (TID) (morning, midday, and evening) for up to 7 days. Patients also use a journal to document symptoms, time of inhalation, and medication use TID for up to 7 days.
GROUP II: Patients inhale 7 drops of chamomile essential oil and complete journal as in group I.
GROUP III: Patients inhale 7 drops of ginger essential oil and complete journal as in group I.
GROUP IV (CONTROL): Patients inhale 7 drops of almond essential oil and complete journal as in group I.
Trial PhaseNo phase specified
Trial Typesupportive care
Lead OrganizationOhio State University Comprehensive Cancer Center
Principal InvestigatorAmber Williams