Auricular Point Acupressure for the Treatment of Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors
- Pre- and postmenopausal women with a history of breast cancer (BC)
- Currently receiving aromatase inhibitors (AIs) per chart documentation
- Able to read and write English
- Have joint pain attributable to AI
- Metastatic BC
- Completed cytotoxic chemotherapy or radiation therapy less than 4 weeks prior to enrollment
I. To develop a smartphone application (app) so that breast cancer survivors (BCS) can learn auricular point acupressure (APA) to self-manage aromatase inhibitor musculoskeletal symptoms (AIMSS).
II. To examine clinical outcomes of the APA on AIMSS between three groups of BCS who will receive: (1) APA app with in-person training; (2) APA app only for self-learning; and (3) education to control time and attention.
III. To explore the central and peripheral modulatory analgesic effects of APA on AIMSS among three groups of BCS with AIMSS.
OUTLINE: Participants are randomized to 1 of 3 arms.
ARM I: Participants receive in-person training on APA once weekly and use APA smartphone app for 4 weeks.
ARM II: Participants use APA smartphone app for 4 weeks.
ARM III: Participants receive educational intervention to control time and attention for 4 weeks.
After completion of study, participants are followed up monthly for 3 months.
Trial Phase Phase O
Trial Type Treatment
Johns Hopkins University / Sidney Kimmel Cancer Center
Chao Hsing Yeh
- Primary ID J17176
- Secondary IDs NCI-2019-06178, IRB00158622, CRMS-68017
- Clinicaltrials.gov ID NCT03697200