This phase I trial evaluates tele interpersonal psychotherapy (tele-IPT) and tele-pharmacotherapy for the treatment of depression in patients with stage I-III breast cancer. Telehealth, also referred to as telemedicine or e-medicine, is the remote delivery of healthcare services over the telecommunications infrastructure without having to come in person for the visit. Interpersonal psychotherapy is a brief treatment that focuses on how life events (such as developing breast cancer) affect mood, and how mood can affect the handling of life events. Serotonin reuptake inhibitors, like venlafaxine (Effexor) and escitalopram (Lexapro) are the most widely used type of antidepressant medications. Using tele-IPT or tele-pharmacotherapy may decrease depression symptoms in patients with stage I-III breast cancer.
Additional locations may be listed on ClinicalTrials.gov for NCT04973930.
Locations matching your search criteria
United States
New York
New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterStatus: Active
Contact: John C. Markowitz
Phone: 646-774-8098
PRIMARY OBJECTIVES:
I. Assess Irving Center major depressive disorder (MDD) prevalence and reasons patients accept or decline randomization.
II. Accept randomization sufficiently to enroll N=20 in one year, report >= 80% treatment satisfaction, and improve on standardized measures of MDD, life quality, and C-reactive protein, an inflammatory marker associated with both diagnoses.
OUTLINE: Patients are assigned to 1 of 2 arms.
ARM I: Patients undergo tele-health interpersonal psychotherapy (IPT) on study. Patients also undergo blood sample collection, and complete an interview on study.
ARM II: Patients receive tele-pharmacotherapy consisting of venlafaxine orally (PO) or escitalopram PO on study. Patients also undergo blood sample collection, and complete an interview on study.
Lead OrganizationNYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
Principal InvestigatorJohn C. Markowitz
